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Rats fed with B12 deficient diet triggered NASH through activation of pro-inflammatory pathways with an imbalanced release of IL- 1, IL- 10, and MCP1 [19]

In this study, the authors show that soluble albumin can rescue proliferation of KRastransformed cells in glutaminelimited conditions

In that pathological model, plasma homocysteine accumulation was mainly attributed to increased homocysteine production from methionine but not impaired homocysteine conversion to cysteine

As a secondary compound, ferulic acid and its derivatives can bind with copper and iron and avoid the generation of toxic hydroxyl radicals, which direct cellular damage (Zduska et al., 2018)

doi:10.1016/j.clnesp.2017.01.002

and G1, G2 etc.: designate peptide functional groups in glutathione and the corresponding G-site ligands of the glutathione 5-transferases, respectively G-site: glutathione-binding site H-site: hydrophobic electrophile-binding site