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While more research is needed, this highlights the importance of moderation

TZDs activate PPAR to promote adipogenesis and fatty acid uptake, increase glucose utilization and decrease glucose production, and subsequently enhance insulin sensitivity by upregulating genes involved in lipid metabolism, such as CD36, FABP4 , and LPL (395)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 435.Scheller EL, Song J, Dishowitz MI, Soki FN, Hankenson KD, Krebsbach PH

Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFB, autophagy, inflammation and oxidative stress