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They state It is clear that serum thyroid hormone and thyroid stimulating hormone concentrations cannot be used with any degree of confidence to classify patients as receiving satisfactory, insufficient, or excessive amounts of thyroxine replacement The poor diagnostic sensitivity and high false positive rates associated with such measurements render them virtually useless in clinical practice Further adjustments to the dose should be made according to the patients clinical response. Similar results were observed by Meier et al

Penn, D., Schmidt-Sommerfeld, E., and Pascu, F

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114 In another meta-analysis that pooled findings from eight randomized controlled trials, PNE was found to moderately reduce pain intensity but did not reduce fibromyalgia impact, catastrophizing, or anxiety

J Urol 2004