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Description
Chemical research in toxicology 25 , 94100, doi: 10.1021/tx200242a (2012)

PMID 15209499

Lacking protective histones, and having less efficient DNA repair mechanisms, mtDNA is ten times more prone to mutations than nuclear DNA
Sirivibulkovit K, Nouanthavong S, Sameenoi Y

Molecular basis for the deficiency in humans of gulonolactone oxidase, a key enzyme for ascorbic acid biosynthesis

On the other hand, a hot shower might give you the relief you are seeking after a long busy day