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J Pineal Res 42:297309 [DOI] [PubMed] [Google Scholar] Lee K, Choi GH, Back K (2017) Cadmium-induced melatonin synthesis in rice requires light, hydrogen peroxide, and nitric oxide, key regulatory roles for tryptophan decarboxylase and caffeic acid O-methyltransferase

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Studies meeting all four criteria were classified as high quality and given primary evidential weight in the synthesis

particularly inclusion of "among others"... Response: We have replaced this sentence with: While these three components are all directly related to ghrelin, one cannot deny the complex interrelationships between ghrelin and the multitude of other systems beyond simply the typical feeding circuitry of this peptide. Line 365-6: Statement "In addition to this, similar situations that lead to drug relapse also lead to relapse in dieting individuals (Nair et al., 2011)" is confusing

Lim, S.-Y., Hong, K.-H., Kim, D.I., Kwon, H
