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In this case, however, one would expect a greater ratio of the rate constants of [Ca 2+ ]i re-uptake upon application of 10 mM caffeine or by electrical stimulation 27 , in which Ca 2+ clearance from the cytosol is dependent mainly on the NCX and the SR Ca 2+ ATPase plus NCX, respectively 28

doi: 10.3390/antiox10121859, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 60.Wu S, Liao X, Zhu Z, Huang R, Chen M, Huang A, et al

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Due to the circadian systems propensity to be modulated by important environmental cues including exposure to bright light, eating, social behavior, exercising and activity schedules, DLMO patterns have been shown to reliably predict circadian timing and help clinicians more accurately assess sleep behavior and sleep phase shifts that can result in poor concentration, development, productivity, and diminished cognitive performance (Murray et al., 2017), (Burgess et al., 2016