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In tumor-bearing mice, liproxstatin-1 enhances NK-cell viability and antitumor activity by pharmacologically inhibiting ferroptosis

a control study using the normal group

Neurosci Lett 764: 136221, 2021

Michino H, Araki K, Minami S, Takaya S, Sakai N, Miyazaki M, Ono A, Yanagawa H

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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care