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OH attacks thymine or deoxyguanosine bases to generate 5-hydroxy-6-hydrothymine or 8-hydroxy-2'-deoxyguanosine (8-OHdG)

Obviously, it is impossible to determine whether the amount found in these samples reflects a pharmacological dosage (Table 2)

Post-mortem studies of ASD patient brains have revealed downregulation of both GAD65 and GAD67 in the superior temporal gyrus, potentially disrupting normal GABA synthesis in the brains of individuals with ASD (38)

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