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SOD2 encodes superoxide dismutase two that neutralizes O 2 - generated during oxidative phosphorylation ( SOD2 polymorphism, rs4880 located in exon 2, introduces a T to C substitution at position 2,734, resulting in the SOD2 Ala16Val genotype

A systematic review of randomized controlled trials found that NAC improved ovulation and pregnancy rates compared to placebo in women with PCOS, though the authors noted variability in study quality.66 More recent meta-analytic research continues to evaluate NAC across both reproductive and metabolic outcomes, suggesting it may offer measurable benefits for some individuals particularly when ovulatory dysfunction and metabolic stress are present.67 You can explore how NAC is used in PCOS research and see our top-rated options in our complete guide to NAC supplements

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[DOI] [PMC free article] [PubMed] [Google Scholar] 153.Wheeler A.P., Bernard G.R

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Previously, no phenotypic or protective effect of EGT could be shown in S