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The results of once daily administration of the peptide for 12 weeks showed that the drug tripled weight loss when compared to placebo and that the rate of weight loss remained steady during the trial period

While these results are promising, they are still in the early stages of testing

Inside cells it directly supports mitochondrial energy production, fuels sirtuin-mediated longevity pathways and provides the substrate PARP enzymes need to repair DNA

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This paradox may be explained by the increased insulin resistance and the compensatory intra-portal hyperinsulinemia causing increased hepatic GH sensitivity that increases serum IGF-I and blunts pituitary GH secretion via the negative feedback loop