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Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (review)

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Lincoff A.M., Brown-Frandsen K., Colhoun H.M., Deanfield J., Emerson S.S., Esbjerg S., Hardt-Lindberg S., Hovingh G.K., Kahn S.E., Kushner R.F., et al

Breast cancer, endometrial cancer, and cardiovascular events in participants who used vaginal estrogen in the Womens Health Initiative Observational Study

These changes were significant at 4-h and 24-h time-points for PLG-dopa-A-GSH and 3-PLG-ibu-A-GSH, respectively

However, selective antagonism of D2-like receptors, specifically D3, can reverse diabetes-induced glomerular hyperfiltration (Luippold et al., 2000), and D3 antagonism also mediated beneficial changes in renal morphology and albuminuria in a model of type 2 diabetes (Gross et al., 2006)

Preclinical research suggests that luteolin effectively exerts antidepressant and neuroprotective effects by inhibiting monoamine neurotransmitter reuptake to increase their levels in the brain (Fig