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CPT1A is the critical rate-limiting enzyme in FAO, responsible for transporting fatty acids from cytoplasm to mitochondria for oxidation

In support of this potential role in DKD pathogenesis are the studies by Ng et al [187] and Sirolli et al [188]: The first study demonstrated an increase in nonanoylcarnitine and 2,6 dimethylthetanoylcarnitine in the urine of DKD patients

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10.1038/nrneurol.2016.68 63

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