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Eur J Gastroenterol Hepatol (2014) 26(7):72532.10.1097/MEG.0000000000000104 160 ValentiniLWirthEKSchweizerUHengstermannSSchaperLKoernickeTet alCirculating adipokines and the protective effects of hyperinsulinemia in inflammatory bowel disease

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Finally, KGMs promotion of beneficial bacteria offers systemic benefits, as its ability to proliferate Akkermansia muciniphila in HFD murine models enhances insulin sensitivity and reduces systemic inflammation [72,104]