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Inhibiting NNMT increases NAD+ levels in fat cells, Justin Kitchens, FNP-C Functional Medicine Practitioner Board-certified Family Nurse Practitioner specializing in peptide therapy, hormone optimization, medical weight loss, and regenerative wellness

It is widely available through licensed pharmaceutical suppliers and is the diluent most commonly specified in UK trial protocols and compounding guidance from the Specialist Pharmacy Service (SPS)

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In contrast, the tenfold increase in vitamin D (7.5 to 75 g) did not consistently result in higher serum vitamin D concentrations in the Optimum 2.0 group throughout follow-up