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Description
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The results show that, with an average intracellular concentration of pyruvate (150M), elimination of 95% H2O2 at normal to pathological concentrations (0.0150M) requires 141185min (2.43hour)

In agreement with this, treatments for some IEMs aim to mitigate overstimulation of N-methyl-D-aspartate (NMDA) receptors by NMDA receptor antagonists and to reduce the levels of the accumulated metabolites that activate these receptors

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