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In addition, the Trx system can interact also with the peroxiredoxins (Prxs), which constitute a novel family of thiol-specific peroxidases that rely on Trx as the hydrogen donor for the reduction of hydrogen peroxides and lipid-hydroperoxides (16)

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Astrocyte activation and reactive gliosisa new target in stroke

Oral 5-Amino-1MQ can face limitations due to variable bioavailability, degradation in the gastrointestinal tract, and first-pass metabolism in the liver

These results support the hypothesis that the T2-induced 15LO1 pathwayinduced alteration of intracellular redox balance enhances T2 inflammatory responses ex vivo