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Hypertension occurrence is often accompanied by gut microbiota imbalance, including decreased diversity, altered enterotype distribution, and variation in bacterial populations, and it is thought that certain types of gut bacteria may produce substances that can affect blood pressure

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Capsaicin 8% dermal patches showed effectiveness comparable to centrally acting agents, like pregabalin, with potentially fewer systemic side effects, faster onset of action, and higher treatment satisfaction [97]