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GPx1-deficient mice had excess generation of hydrogen peroxide in pancreatic islets that correlated with increased p53 and p38 MAPK phosphorylation, decreased islet cell mass, and hypoinsulinemia

10.1038/35083070 137 KarathanassisD.StahelinR

J Biol Chem 274:636673 Chae HZ, Kang SW, Rhee SG (1999) Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin

The same may be true of prebiotics like Performance Lab Prebiotic but this should die down once your gut microbiome adapts

Nature 603, 672678

In patients with peripheral artery disease, IV glutathione was shown to improve pain-free walking distance and several markers of macro- and microcirculation in a randomized and double-blinded trial