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2012 GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes Cosmetics Study demonstrating GHK-Cu's regulation of antioxidant gene expression and copper-dependent protective mechanisms in skin tissue

Excess urinary porphyrins (which share a similar structure with hydroxocobalamin) have also been implicated

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Please note, not all B12 is created equally, and high quality B12 in methylcobalamin form is crucial

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