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Description
At the high affinity site 2, the A and C helices of leptin engage several loops in the CHR2 (D4 and D5) of LepR, burying 750 2 of surface area (Fig
Anitua E, Muruzabal F, Pino A, Merayo-Lloves J, Orive G
Wimmer, R
Tamai I, Yabuuchi H, Nezu J, Sai Y, Oku A, Shimane M et al
doi: 10.1038/nbt0293-187
It is also structurally very similar to two other common organometallic (2) molecules, heme, and chlorophyll (Figure 1), all of which are critical biomolecules for animal and plant life
