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In addition to targeting enzymes in the PPP, NADPH levels can be genetically manipulated through an engineered enzyme called triphosphopyridine nucleotide oxidase (TPNOX) 189 , which converts NADPH and oxygen to NADP and water

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NAC is an amino acid derivative that serves as a direct precursor to glutathione, the body's "master antioxidant." Glutathione is primarily responsible for neutralizing intracellular oxidative stress and detoxifying harmful compounds

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Gamma-glutamyl transpeptidase in glutathione biosynthesis.Methods Enzymol.2005;401:468483

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doi: 10.1016/j.semcdb.2019.05.012

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& Niles, R

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