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J Assist Reprod Genet 30(3):341352

Krzystek-KorpackaMKempiskiRBromkeMANeubauerK

This regulation is accomplished by a complex interplay among transcription factors, hormonal and nutrient signaling pathways, energy status, cell cycle, oxidative stress, hypoxia, availability of vitamin cofactors, and influences from phosphorylation, allosteric modulation, and degradation mechanisms

This panel is as in a , except analysis is of data from MEFs

In these types of experiments there is an increased rate of pancreatic -cell apoptosis, reduced -cell proliferation, and reduced glucose-dependent insulin secretion