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Description
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

Three TCA cycle isozymes generate NADPH: mitochondrial isocitrate dehydrogenase 2 (IDH2) and cytosolic IDH1 and malic enzyme (ME1)

There is no published evidence that it would

doi: 10.1007/s00198-009-1059-y

That said, water weight that doesnt go away may be a sign of edema, which could require medical treatment

et al., 2025) (Figure 2B)
