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In the latter study, a significantly lower dose of human menopausal gonadotropin (HMG) was required in these women, which is expected given that women with PCOS typically have high serum anti-mullerian hormone (AMH) levels and are more prone to developing ovarian hyperstimulation syndrome (OHSS)

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Other supportive evidence is the correlation of the rate of transport of a given substance with transcellular electrical resistance, in which lower transport rates of substances assumed to be transported paracellularly are observed in high-resistance, tight epithelia, although electrical resistance and the transport of marker molecules do not always coincide