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Cytokines such as platelet-derived growth factor, transforming growth factor- (TGF-), TNF-, and Interferon also play a crucial role in the pathogenesis of liver fibrosis and cirrhosis (Zhou et al., 2014)

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LDH is a kind of significant enzyme involved in anaerobic glycolysis and gluconeogenesis, the increase of which reflects abnormal cell morphology, vitality, and migration ability [39, 40]

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