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Before the discovery of B12 people used to eventually die of it hence the name Pernicious Anaemia

PMID 6387014

Certain individuals should not receive B12 injections without explicit medical clearance or should avoid them altogether

Regular drinkers may have a higher threshold for intoxication and overdose, though this does not eliminate the risk of severe poisoning or death

8,9 In studies concerning temperature measurements in narcolepsy patients, an altered diurnal temperature profile has been demonstrated in both core body and skin temperature

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