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In addition to working as an electron carrier, the oxidized cyt c also serves as a scavenger of reactive oxygen species (ROS) (Wang et al., 2003), a cardiolipin peroxidase (Kagan et al., 2005), and an apoptosis activator once released to the cytosol (Ow et al., 2008)
Peptides are best understood as targeted signaling molecules
Typical cycle: 812 weeks on, followed by 48 weeks off
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The specific binding of bevacizumab to VEGF-A protein reduces VEGF protein levels by limiting the formation of new blood vessels (Genovese and Impellizzeri 2022)
