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Primary drug resistance refers to the intrinsic resistance of tumor cells to a particular anticancer drug, regardless of exposure to the drug

A.BegyC.ChandrasekharappaS.et al

M2 activates STAT6 and STAT3 to drive polarisation by cytokines (IL-4, IL-13, IL-10, etc.), mediates ROS-induced tissue damage, and has anti-inflammatory and anti-tumor activities [21-23]

[DOI] [PubMed] [Google Scholar] 74.Duncan M.J., Tallis J., Wilson S., Clarke N.D
McKusick V, Rasooly R

Arthritis IV: Medications are delivered intravenously to reduce the symptoms of rheumatoid arthritis