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Current strategies to combat this include not only modification of the AAV capsid and optimization of the viral genome, but also the use of immunosuppressive therapy [153]

Start with lower doses to assess tolerance and gradually increase over 2-3 weeks

289 In addition, CD8 + T cell activation and recruitment were increased in the JHU-083 treatment model, and MDSCs generation and recruitment were significantly inhibited

Scientists still arent sure why this happens and havent yet developed a cure, but we know that inflammation is a huge factor and that oxidative stress is often the culprit

The GSH in the dorsolateral prefrontal cortex is depleted significantly in schizophrenia patients [27]

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