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Description
That potency is exactly why the dose is not started high: the entire point of a titration protocol is to introduce the compound at a low, well-tolerated level and raise it in slow, roughly four-week steps so the gastrointestinal system can adapt

pERK signaling and, collectively with previous mutagenesis data, offer evidence that the conformations linked to these different signaling pathways are, in many ways, mutually exclusive

Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers

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