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Finally, we examined the effect of combining mutations on Rb and found that LxCxE, RxL, and helix mutations were additive (Figures 1K, 1L, and S2G)

10.1016/j.lfs.2004.08.025 98 ZhangZ.PanY.ZhaoY.RenM.LiY.LuG.et al (2021)

C.2000N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.1519(May 2000),846861,0002-9262 13

However, further research is needed to fully understand these mechanisms and identify potential therapeutic targets

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