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The HSA also pointed out that the hydroquinone found was three times higher than the concentrations found in the products used for skin treatments, and the substance could result in changes in skin colour and hypersensitivity reactions such as rashes, redness, tingling and burning of skin

(Zhang et al., 2013a)

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H 2 O 2 can also directly modulate the activities of several antioxidants, protein kinases, and transcriptional regulators for redox regulation