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In SMMC-7721 cells, GA augmented caspase-3, caspase-9, and ROS production, reducing mitochondrial outer membrane permeabilization (MOMP) production, and eventually causing apoptosis

(** The data in this list are not 100% accurate

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Likewise, significant decreases in GSH/GSSG ratio in combination treatments compared to TGR inhibitors alone were also seen

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Molecular Basis of Disease, Elsevier 1739 , 525, doi:10.1016/j.bbadis.2004.08.004 (2004)