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One trial evaluated TB4 for heart health, finding that the peptide could protect and repair the heart in patients with acute myocardial infarction, and a separate trial found that TB4 improved outcomes during congenital heart surgery.21 The review also mentions a few clinical trials related to eye health, with results showing that TB4 can reduce eye dryness, relieve ocular discomfort, lower inflammation in the conjunctiva, and more

Adding cagrilintide to tirzepatide Theoretical protocol (not clinically studied): If on tirzepatide 10-15mg: Stable on tirzepatide for 4+ weeks Continue tirzepatide at current dose Add cagrilintide 0.6mg weekly Standard cagrilintide titration to 2.4mg Rationale: Tirzepatide is dual GIP/GLP-1 (very powerful alone) Adding amylin pathway could theoretically enhance No clinical data on this combination Uncertain if additional benefit over tirzepatide alone Concerns: GI side effects may be severe (both slow gastric emptying) Tirzepatide already produces 15-22% weight loss alone Unclear if cagrilintide adds meaningful benefit Expensive combination Verdict: Wait for clinical data

N., Song, Y., Chen, W., Wang, G., Edden, R

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Because of the normally short survival of leukocytes and platelets, however, most individuals with G6PD deficiency do not manifest impairment of phagocytosis or bactericidal activity of granulocytes
