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This difference may affect response patterns

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-Carotene increases protein expression of nuclear NRF2 and upregulates downstream targets containing antioxidant response elements (ARE) such as NADPH quinone oxidoreductase 1 (NQO1) and haeme oxygenase-1 (HO-1), thereby reducing oxidative damage to neurons 142

J Oral Sci

We will discuss several interesting aspects of the two figures

The net effect of these concerted actions of nNOS and eNOS is increased inotropy (contractile force) of the heart