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Necroptosis can also be materialized as a result of activation of the signaling pathways, due to DNA damage, which leads to the release of apoptosis-related factors from the mitochondrial intermembrane space, followed by the activation of the DNA damagerelated enzyme poly(ADP-ribose) polymerase (PARP) [213]

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Despite its use over the past seven decades, multiple placebo-controlled designs have shown no significant improvement in pain, degree of curvature, plaque size, or ability to have intercourse

Front Neurol 13:877772 [DOI] [PMC free article] [PubMed] [Google Scholar] 128.Tedjasukmana R, Budikayanti A, Islamiyah WR, Witjaksono A, Hakim M (2022) Sleep disturbance in post Covid-19 conditions: prevalence and quality of life

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