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Insufficient insulin secretion and reduced tissue response to insulin impair the complex action of insulin in target tissues, resulting in disturbed metabolism of carbohydrates, lipids, and proteins

[DOI] [PMC free article] [PubMed] [Google Scholar] 431.Cortese-Krott M.M., Fernandez B.O., Santos J.L.T., Mergia E., Grman M., Nagy P., Kelm M., Butler A., Feelisch M

R., Peiser, C., Groneberg, D
Oxidative stress and glutathione in TGF--mediated fibrogenesis


Under general or denatured conditions (such as 8M urea), it can form coordination bonds with transition metal ions such as Ni2+ and Co2+ and selectively bind to metal ions
