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Vitamin B12 is absorbed in our small intestines
& Nakanishi, M
and individual variation in amino acid metabolism
(3) those that are permanently in the reduced state and (4) those that are susceptible to reversible and irreversible oxidation [3]
Treating cells with L-buthionine sulfoximine (BSO), an inhibitor that blocks the synthesis of GSH, renders neuronal SH-SY5Y cells expressing mutant valosin-containing protein (VCP) R487H more susceptible to oxidative stress (Hirano et al., 2015) and increases mutant SOD1 toxicity (Alvarez-Zaldiernas et al., 2016
