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Before administering the intervention, the mice were given swimming treatment for 15min to increase the stress state

All three protocols are effective

About the doctors Albert Khouri, MD Associate professor of ophthalmology Rutgers New Jersey Medical school Newark, New Jersey Daniel Lee, MD Clinical instructor of ophthalmology Wills Eye Hospital Philadelphia, Pennsylvania Janet Serle, MD Professor emeritus of ophthalmology Icahn School of Medicine at Mount Sinai New York, New York References Weinreb RN, et al

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Long-term follow-up of a randomized AAV2-

It promotes NRF2 ubiquitination through the Keap1/NRF2/ARE signaling pathway, induces ROS accumulation, and inhibits the phosphorylation of AktSer473 and mTORSer2448