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Leveraging the relationship between macrophage polarization phenotypes and iron metabolism, therapeutic targeting of TAMs within the TME represents a promising anti-tumor strategy (82)

These findings suggest that immune dysregulation and oxidative imbalance may contribute to the underlying pathophysiology of ADHD, influencing brain development and function

As the primary immune cells in autoimmunity in vitiligo, the differentiation, proliferation, and homeostasis of CD8 + T cells are also influenced by UPR signaling

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Andreeff M , Consoli U, Kleine HD, Engel H, Munker R, El-Tounsi I, Jiang S, Zhao S, Goodacre A, Sanchez-Williams G, Kornblau S, Estey E