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For research purposes, safety data are mainly relevant to dose-finding and study design in experimental models , not as endorsement of any clinical or self-administration use

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[PMC free article] [PubMed] [Google Scholar] 18.Polito A, Intorre F, Andriollo-Sanchez M, Azzini E, Raguzzini A, Meunier N, Ducros V, OConnor JM, Coudray C, Roussel AM, et al

Ideally, blood tests (including full blood count, serum B12, folate, and possibly anti-intrinsic factor antibodies if pernicious anaemia is suspected) should be performed before starting supplements, as supplementation can affect test results