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Development of PI3K/AKT/mTOR pathway inhibitors and their application in personalized therapy for non-small-cell lung cancer
Oxidative stress and heart failure, American journal of physiology
The ATM-Chk2-cell division cycle 25A (Cdc25A)-cyclin-dependent kinase 2 (Cdk2) pathway acts as a genomic integrity checkpoint and guards against radioresistant DNA synthesis ( Activating transcription factor 3 (ATF3) belongs to ATF/cAMP-responsive element-binding protein (CREB) family ( MDM2 is an E3 ubiquitin ligase that carries out the final step in the ubiquitination cascade, catalyzing transfer of ubiquitin from an E2 enzyme to form a covalent bond with a substrate lysine ( Pregnane X receptor (PXR, NR1I2, SXR) belongs to the nuclear receptor superfamily and is mainly expressed in normal liver, small intestine, colon, duodenum, and gall bladder tissues ( In this study, we investigated the role and the mechanism of PXR in the protection of liver and colon cancer cells from IR-induced DDR
Morbidity and mortality in patients with rheumatoid arthritis compared with an age- and sex-matched control population: A nationwide register study
Despite the variation in the incision style, all procedures followed standardized closure techniques to ensure consistency across cases
Disulfide stress: a novel type of oxidative stress in acute pancreatitis
