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Fourth, these inflammatory cytokines elevate ROS/RNS levels, triggering oxidative stress that inflicts damage on mitochondrial DNA, membranes, and the ETC, ultimately culminating in ATP depletion

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Tripathi MK, Kartawy M, Amal H

What follows below is a description of the evidence used by the Work Group to reach is conclusions

Given the role of carnitine transporters in cancer metabolism, targeting these transporters could disrupt FAO and potentially inhibit tumor growth.Carnitine transporters can be exploited for targeted drug delivery, enhancing the efficacy of chemotherapy.Expression levels of carnitine transporters like OCTN2 and CT2 could serve as prognostic markers for certain cancers