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Description
M., Yousaf, A., Fang, W

Furthermore, the systemic neuroinflammation driven by this oxidative stress directly impacts the autonomic nervous system

Histology showed 2.5-fold fibroblast proliferation

Preclinical evidence (strongest) Lee and colleagues (2015, Cell Metabolism ) showed MOTS-c reduced obesity and insulin resistance in mice on a high-fat diet

Oral Investig

Apoptotic signaling, oxidative stress, and mtDNA damage collectively exacerbate neuroinflammation and neurodegeneration (McGovern and Barreto, 2021) propagation in the long term (De Gaetano et al., 2021
