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& Blakney, A

SGLT2 inhibitors enhance fatty acid oxidation and ketogenesis, potentially reducing renal accumulation of long-chain acylcarnitines [172], while metformin attenuates the acute eGFR decline induced by SGLT2 inhibitors [173]

Two 20242025 meta-analyses pooling data across multiple trials confirmed statistically meaningful improvements in standardized erectile-function scores and penile blood flow

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doi: 10.1167/tvst.10.12.7

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