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Ultra performance liquid chromatography (UPLC) analysis was performed on an Agilent 1290 series instrument
The enzyme 4-phosphopantetheinyl transferase catalyzes the hydrolysis of coenzyme A to 3,5-adenosine diphosphate and 4-phosphopantetheine, and the transfer of the 4-phosphopantetheinyl moiety to a serine residue at the active site of ACP, converting biologically inactive apo-ACP into active holo-ACP
Nets are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
In parallel, high-priority synthetic lethal targets were also selected as part of the MetDP framework
2021;131(19): e148286
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