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Ann Intern Med 98(2):151-5, 1983

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Location: Enugu, Nigeria

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While tumor suppressors are usually inactivated by frameshift or nonsense mutations, the most frequent mechanisms by which the wild-type p53 is inactivated in primary human tumors are missense mutations in the coding region with a strong predominance for exons 49

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The therapeutic effects of traditional Chinese medicine (TCM) and natural products (NPs) on liver diseases are expected to be inextricably linked to the targeted regulation of gut microbial dysbiosis

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Maeda M, Takeshima H, Iida N, Hattori N, Yamashita S, Moro H, et al

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Small protein folds at the root of an ancient metabolic network

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