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IGF-II/IGF-I Receptor Pathway Up-Regulates COX-2 mRNA Expression and PGE2 Synthesis in Caco-2 Human Colon Carcinoma Cells

Both constructs are produced with N-terminal maltose binding protein (MBP) and C-terminal histidine tag for high-yield bacterial expression and for simple affinity-resin purification

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Grade 3 or 4 neurologic toxicity: This drug should be permanently discontinued

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