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Description
c-Myc directly activates the genes involved in nucleotide synthesis, including thymidylate synthase for pyrimidine metabolism, inosine monophosphate dehydrogenase 1 and 2 for purine metabolism, and phosphoribosyl pyrophosphate (PRPP) synthetase 2 for the production of PRPP, which is a common precursor for purine and pyrimidine nucleotides
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Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
[DOI] [PubMed] [Google Scholar] 129.Lapsley J., Hayes G.M., Janvier V., Newman A.W., Peters-Kennedy J., Balkman C., Sumner J.P., Johnson P
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