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Jessica Secratt and Tory Lander RASP Academic Spotlight Dr

Bile acid modulators represent another class of drugs that can influence cardiovascular outcomes by altering gut microbiota composition and function

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Preferential substrates of peroxisomal -oxidation are very long-chain fatty acids (which are not substrate of CPT-1 and thus cannot enter mitochondria), pristanic acid (2,6,10,14-tetramethylpentadecanoic acid), di- and trihydroxycholestanoic acid, the tetracosaenoic acid (C24:6n-3), and long-chain dicarboxylic acids [19, 6668]

2019;24 doi: 10.3390/molecules24183251

Source: 2026 ACC/AHA/Multisociety Guideline on the Management of Dyslipidemia, Table 14 Dietary factors Metabolic factors Drugs Physiological LDL indicates low-density lipoprotein